IP6 (Inositol Hexaphosphate / Phytic Acid)
The myo-inositol with 6 phosphate groups. A natural iron chelator with surprising anti-cancer and bone-density evidence.
Strong mechanism evidence (iron chelation, oxidant blocking). Moderate evidence for cancer adjunct (animal and small human trials), kidney stone prevention, and bone density support. Effects: 8–12 weeks.
Make it part of your plan
Reference dose
800–2,400 mg IP6 daily, often combined with 200–600 mg inositol.
Choose a stack first, or enter your own amount here. Reference information is not a personal prescription.
IP6 (inositol hexaphosphate, phytic acid) is the storage form of phosphorus in plants and seeds. In supplement form (often paired with inositol — 'IP6 + Inositol' branded products), it acts as a chelator of excess iron, blocks the formation of free radicals from Fenton chemistry, and shows anti-cancer activity in animal and small human trials (most strongly with breast cancer adjunct work by AbulKalam Shamsuddin). Also supports bone density and kidney stone prevention. Different from regular inositol — read the label.
- Form
- IP6 + Inositol blends (Cell Forte, IP-6 International, Jarrow). Avoid generic 'phytic acid' without standardisation.
- Timing
- Empty stomach for chelation effect (away from minerals). PM common.
- Schedule
- Daily.
- Side effects
- Generally well-tolerated. Can cause mineral deficiencies (especially iron, zinc, calcium) at high chronic doses — take separate from mineral-rich meals.
- Interactions
- Iron, zinc, calcium, magnesium — chelates and reduces absorption. Take 2 hours from mineral-containing meals or supplements.
- Contraindications
- Iron-deficiency anemia. Active osteoporosis without mineral monitoring. Pregnancy / breastfeeding.
- Lab markers
- Ferritin (iron status), mineral panel if running long-term.
- Food sources
- Whole grains, legumes, nuts, seeds — naturally high in phytic acid (often considered an 'anti-nutrient' for mineral absorption, beneficial in some contexts).
Pairs with
Inositol (the partner). Quercetin, curcumin, vitamin C (antioxidant network).
Where to buy
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