← Blood tests
Anti-Centromere
Specialistalso —
What it isAutoantibodies targeting centromere proteins during cell division. Highly associated with limited systemic sclerosis (CREST syndrome).
DoesMarks limited cutaneous systemic sclerosis.
GoodNegative result in someone with Raynaud's or skin tightening argues against limited scleroderma.
BadPositive anti-centromere identifies limited scleroderma and predicts pulmonary hypertension as a major complication.
- Standard
- Negative.
- Optimal
- Negative (lower is good)
- Modifiers
- Stable over time.
How to optimize
- Lifestyle
- Cold protection for Raynaud's; quit smoking.
- Diet
- —
- Supplements
- Omega-3 EPA+DHA (2–4g/day) may help vascular tone.
- Peptides
- —
- Drugs
- Calcium channel blockers for Raynaud's; treatment of pulmonary hypertension if present.
Reference ranges are general adult lab norms; optimal ranges are editorial picks from the longevity literature — not medical advice. Always interpret results with your physician.
within Autoimmune