Kisspeptin

Hypothalamic neuropeptide that triggers GnRH release — restores natural sex-hormone signaling upstream.

Kisspeptin sits at the very top of the hormone chain — it's the signal that tells your brain to kick off the whole cascade that ends in testosterone (or estrogen) production. Instead of replacing a hormone, it restarts your own factory from upstream, which is why it's used to restore natural testosterone, support fertility, and recover the HPG axis after it's been suppressed (e.g., post-cycle). It also lifts libido without the melanocortin side effects of the tanning peptides — a cleaner "switch the system back on" approach.

Dose

100–300 mcg subQ daily.

Reconstitute

10 mg + 2 mL = 5 mg/mL. 4 units = 200 mcg.

Schedule

4–8 week cycles, especially during or after HPG suppression.

Half-life

~30 minutes.

Timing

AM.

Risks

Minimal. Transient receptor desensitization at very high doses.

Educational reference — not medical advice. Many peptides are not approved for the uses discussed; verify status in your jurisdiction and decide anything here with a qualified clinician.

within Sexual Health & Reproductive