Fibrinogen
Advanced wellnessalso factor i
What it isFibrinogen is a soluble plasma protein made by the liver that is converted to fibrin during clot formation. It also functions as an acute-phase reactant that rises with inflammation.
DoesForms the structural scaffold of blood clots; contributes to blood viscosity.
GoodA mid-range level provides adequate clotting capacity without thrombotic excess.
BadHigh fibrinogen increases blood viscosity and clot risk, predicting heart attack, stroke, and venous thromboembolism. It also reflects chronic systemic inflammation.
- Standard
- 200–400 mg/dL.
- Optimal
- 200–280 mg/dL (lower is good within range)
- Modifiers
- Rises with smoking, obesity, stress, infection, pregnancy.
How to optimize
- Lifestyle
- Quit smoking, regular aerobic exercise, weight loss, stress management.
- Diet
- Mediterranean pattern; cut ultra-processed food; add fatty fish, olive oil.
- Supplements
- Omega-3 EPA+DHA (2–4g/day), curcumin (500mg 2×/day), nattokinase (2000 FU/day), vitamin E (mixed tocopherols, 200 IU/day).
- Peptides
- —
- Drugs
- Fibrates lower fibrinogen modestly; statins reduce it through anti-inflammatory effect.
Reference ranges are general adult lab norms; optimal ranges are editorial picks from the longevity literature — not medical advice. Always interpret results with your physician.
within Cardiovascular & BP