← Blood tests
Anti-CCP (Cyclic Citrullinated Peptide)
Advanced wellnessalso acpa
What it isAnti-citrullinated protein antibodies target proteins that have undergone citrullination — a post-translational modification.
DoesMarks rheumatoid arthritis with high specificity.
GoodA negative anti-CCP largely rules out rheumatoid arthritis.
BadPositive anti-CCP confirms rheumatoid arthritis, often before clinical disease appears, and predicts more aggressive disease and joint erosion.
- Standard
- <20 U/mL.
- Optimal
- 0–20 U/mL (lower is good)
- Modifiers
- Smoking strongly drives anti-CCP positivity in genetically susceptible individuals; periodontal disease may contribute.
How to optimize
- Lifestyle
- Quit smoking; oral hygiene; anti-inflammatory lifestyle.
- Diet
- Mediterranean pattern; identify food sensitivities.
- Supplements
- Omega-3 EPA+DHA (2–4g/day), curcumin, vitamin D3.
- Peptides
- BPC-157, thymosin alpha-1.
- Drugs
- Methotrexate, biologics for confirmed RA.
Thymosin Alpha-1Omega-3 (EPA/DHA)Vitamin D3Curcumin (Turmeric)BPC-157
Reference ranges are general adult lab norms; optimal ranges are editorial picks from the longevity literature — not medical advice. Always interpret results with your physician.
within Autoimmune