SS-31 (Elamipretide)

Mitochondria-targeted peptide that binds cardiolipin and rescues inner-membrane function.

Where MOTS-C signals the mitochondria, SS-31 physically goes inside them. It binds cardiolipin, a fat that holds the inner membrane's energy-producing machinery in the right shape; in aged or damaged cells that machinery turns sloppy and leaky, and SS-31 restores it. The payoff is more efficient energy production with less oxidative "exhaust" — which is why it's been studied for heart failure, mitochondrial muscle disease, and the age-related decline in muscle power. It's a repair tool for tired cellular engines.

Dose

5–10 mg subQ daily.

Reconstitute

30 mg + 3 mL = 10 mg/mL. 100 units = 10 mg.

Schedule

30–60 day cycles.

Half-life

~2–4 hours.

Timing

AM.

Risks

Injection-site reactions. Expensive.

Educational reference — not medical advice. Many peptides are not approved for the uses discussed; verify status in your jurisdiction and decide anything here with a qualified clinician.

within Metabolic & Mitochondrial