MOTS-C

Mitochondrial-derived 16-residue peptide that activates AMPK — the closest thing to an injectable exercise mimetic.

MOTS-C is a signal your mitochondria release during exercise and metabolic stress — it flips on AMPK, the cellular "energy sensor" that tells the body to burn fuel, take up glucose, and clean house. Injecting it essentially mimics some of the metabolic signalling of a workout: better insulin sensitivity, more fat oxidation, improved endurance. Because it tunes up mitochondrial function at the source, it's an ideal "primer" run a month before a fat-loss or repair stack — clean up the engine before you ask more of it.

Dose

5–10 mg subQ, 2–3× per week.

Reconstitute

20 mg + 4 mL = 5 mg/mL. 100 units = 5 mg.

Schedule

8–12 week cycles. Ideal as a primer before fat-loss or repair stacks.

Half-life

Hours.

Timing

AM pre-workout (mimics post-exercise signaling).

Risks

Very mild. Some users report fatigue on the first dose.

Educational reference — not medical advice. Many peptides are not approved for the uses discussed; verify status in your jurisdiction and decide anything here with a qualified clinician.

within Metabolic & Mitochondrial