Sermorelin

GHRH(1-29) — the original, gentler GHRH research peptide. Milder than Tesamorelin.

Sermorelin is the original GHRH fragment — just the first 29 amino acids of natural growth-hormone-releasing hormone, the minimum needed to do the job. It's the gentlest, most physiologic option in the family: it nudges your pituitary rather than hammering it, which makes it a popular entry point for people who mainly want better sleep and recovery without pushing GH hard. The flip side of that gentleness is a very short half-life and milder effects than Tesamorelin, so it's best understood as the easy-going starter GHRH.

Dose

200–500 mcg subQ pre-bed.

Reconstitute

10 mg + 2 mL = 5 mg/mL. 10 units = 500 mcg.

Schedule

5×/week, 12–16 week cycles.

Half-life

~10–20 minutes.

Timing

Pre-bed fasted, ≥3 hours after last food.

Risks

Very mild. Possible injection-site flushing.

Educational reference — not medical advice. Many peptides are not approved for the uses discussed; verify status in your jurisdiction and decide anything here with a qualified clinician.

within Growth Hormone — Natural Release (Secretagogues)