SSA / Ro and SSB / La

Specialist

also

What it isAutoantibodies that target the Ro and La ribonucleoprotein particles. They appear in Sjögren's syndrome and lupus.

DoesMark Sjögren's syndrome (dry eyes and mouth from autoimmune exocrine gland attack) and lupus subsets.

GoodNegative results argue against Sjögren's in someone with sicca symptoms.

BadPositive results confirm Sjögren's syndrome or, in pregnancy, predict risk of congenital heart block in the fetus.

Standard
Negative.
Optimal
Negative (lower is good)

How to optimize

Lifestyle
Stress management; eye protection.
Diet
Mediterranean pattern; hydration.
Supplements
Omega-3 EPA+DHA (2–4g/day), vitamin D3.
Peptides
Drugs
Hydroxychloroquine for Sjögren's; pilocarpine for dry mouth.