Anti-Smith (Sm)
Specialistalso —
What it isAutoantibodies that target Smith nuclear ribonucleoprotein, one of the most specific markers for systemic lupus.
DoesConfirms lupus diagnosis when positive.
GoodNegative excludes one specific lupus marker but doesn't rule out the disease.
BadPositive anti-Sm is highly specific for lupus and supports diagnosis even when ANA pattern is ambiguous.
How to optimize
- Lifestyle
- Sun protection; stress management.
- Diet
- Mediterranean pattern.
- Supplements
- Omega-3 EPA+DHA (2–4g/day), vitamin D3.
- Peptides
- —
- Drugs
- Hydroxychloroquine, immunosuppressants for lupus.
within Autoimmune