Microalbumin / Creatinine Ratio (urine)

Advanced wellness

also uacr, acr

What it isA urine test measuring small amounts of albumin that have leaked through the glomerulus into urine, normalized to urine creatinine. The kidney filter normally holds back almost all albumin.

DoesDetects early kidney damage at the glomerular barrier — a leaky filter.

GoodA very low ratio confirms an intact filtration barrier and predicts cardiovascular and kidney longevity.

BadMicroalbuminuria is the earliest detectable sign of diabetic or hypertensive kidney damage and an independent cardiovascular risk marker.

Standard

<30 mg/g normal; 30–300 microalbuminuria.

Optimal

0–5 mg/g (lower is good)

Modifiers

Rises transiently with exercise, fever, infection, and dehydration.

How to optimize

Lifestyle: Manage blood pressure aggressively, control blood sugar, weight loss, Zone 2 cardio, quit smoking.
Diet: Lower sodium; Mediterranean pattern; moderate protein.
Supplements: Omega-3 EPA+DHA (2–4g/day), CoQ10 (100–200mg/day), vitamin D3.
Peptides: —
Drugs: ACE inhibitors and ARBs reduce albuminuria; SGLT2 inhibitors and finerenone provide additional protection in diabetics.

within Kidney