Lymphocyte-to-Monocyte Ratio (LMR)

Specialist

also

What it isThe ratio of lymphocytes to monocytes — adaptive immune competence against innate inflammatory drive.

DoesCaptures immune balance in a single number.

GoodA high ratio signals strong adaptive immunity relative to inflammatory activity and predicts better cancer outcomes.

BadA low ratio tracks chronic inflammation and worse prognosis in cancer, cardiovascular disease, and sepsis.

Standard
3–6.
Optimal
4.0–6.0 (higher is good)
Modifiers
Falls with chronic inflammation and infection.

How to optimize

Lifestyle
Sleep, stress management, resistance training.
Diet
Mediterranean pattern; adequate protein.
Supplements
Vitamin D3 (target 60–80 ng/mL), zinc, omega-3 EPA+DHA (2–4g/day).
Peptides
Thymosin alpha-1, thymalin.
Drugs
Treat underlying cause.