Monocyte-to-HDL Ratio (MHR)

Specialist

also

What it isA calculated ratio of monocytes to HDL cholesterol that captures the balance between vascular inflammatory drive and reverse cholesterol transport.

DoesCombines two cardiovascular predictors into a stronger composite.

GoodA low MHR signals balanced vascular biology.

BadElevated MHR predicts cardiovascular events, metabolic syndrome, and atherosclerosis progression.

Standard
Lab-specific.
Optimal
5–10 (lower is good)
Modifiers
Rises with chronic inflammation and metabolic syndrome.

How to optimize

Lifestyle
Zone 2 cardio; quit smoking; weight loss; resistance training.
Diet
Mediterranean pattern; cut refined carbs and trans fats.
Supplements
Omega-3 EPA+DHA (2–4g/day), curcumin (500mg 2×/day), niacin (under supervision).
Peptides
Drugs
Statins.