Ionized Calcium

Advanced wellness

also

What it isThe free, unbound fraction of blood calcium that is biologically active at receptors.

DoesDrives all physiological calcium effects — nerve, muscle, clotting, signaling.

GoodMid-range ionized calcium signals true calcium adequacy regardless of albumin status.

BadProvides the most accurate calcium status, particularly when parathyroid disease is suspected or in critically ill patients with abnormal albumin.

Standard
4.5–5.6 mg/dL.
Optimal
4.8–5.3 mg/dL (narrow target)
Modifiers
Affected by blood pH (acidosis raises ionized fraction).

How to optimize

Lifestyle
Same as total calcium.
Diet
Same as total calcium.
Supplements
Same as total calcium.
Peptides
Drugs
Treat underlying cause.