Corrected Calcium

Routine annual

also albumin-adjusted calcium

What it isA calculation that adjusts total calcium for albumin level. Since most calcium binds to albumin, low albumin reduces total calcium even when the active ionized fraction is normal.

DoesProvides a more accurate estimate of calcium status when albumin is abnormal.

GoodMid-range corrected calcium signals truly intact calcium homeostasis.

BadSame patterns as total calcium, but with confounding from low albumin removed.

Standard
8.6–10.3 mg/dL.
Optimal
9.2–9.8 mg/dL (narrow target)
Modifiers
Only useful when albumin is abnormal; ionized calcium is more accurate when available.

How to optimize

Lifestyle
Same as total calcium.
Diet
Same as total calcium.
Supplements
Same as total calcium.
Peptides
Drugs
Treat underlying cause.