Tribulus terrestris
Traditional Ayurvedic and TCM herb sold for testosterone — but RCTs don't show testosterone elevation. Real effects are on libido and sexual satisfaction (probably via different mechanisms).
Multiple negative trials for testosterone elevation in men. Moderate evidence for libido and sexual function in both sexes. Effects: 4–8 weeks for libido.
Tribulus terrestris (puncture vine) is one of the most-marketed 'testosterone boosters' in supplements — and the marketing is largely wrong. Multiple well-designed trials in men show no significant testosterone elevation. What tribulus does do, with reasonable evidence, is improve libido and sexual satisfaction in both men and women — likely through nitric oxide pathway effects and possibly some central nervous system action. So: useful for sexual function, mostly placebo for testosterone. The Bulgarian variety standardised to protodioscin has the most-studied actives.
- Form
- Bulgarian Tribulus terrestris extract standardised to ≥40% saponins, with specified protodioscin content. Brand: Tribulus 40% (NOW), Vitanol.
- Dose
- 750–1,500 mg/day standardised extract. Split across the day.
- Timing
- With food. AM and midday.
- Schedule
- Cycle: 8 weeks on, 2–4 weeks off.
- Side effects
- Generally well-tolerated. GI upset, sleep disturbance, irritability in some.
- Interactions
- Diabetes medications — mild glucose lowering. Antihypertensives — mild BP effects. Lithium — diuretic effect may alter levels.
- Contraindications
- Pregnancy / breastfeeding. Hormone-sensitive cancers. Active prostate cancer or BPH (unclear safety). Pre-surgery (mild blood pressure effects).
- Lab markers
- Total + free testosterone, estradiol if tracking hormonal effects (mostly to confirm tribulus doesn't change them).
- Food sources
- Not present in everyday food.
Pairs with
Maca, tongkat ali (libido / sexual function combos). L-arginine, L-citrulline (nitric oxide synergy). Zinc, boron (hormonal cofactors).
within Herbs & botanicals