Eggshell Membrane (NEM)
The thin membrane between the eggshell and egg white — concentrated source of collagen, glycosaminoglycans, and other joint-supportive molecules. Small dose, real effect.
Moderate evidence for OA pain and stiffness — Ruff et al. trials show ~30% pain reduction in 30 days. Faster onset than glucosamine. Effects: 1–4 weeks.
Natural Eggshell Membrane (NEM, branded as ESM Technologies' patented form) is a tiny-dose joint supplement — typically 500 mg/day — that delivers a complex mix of collagens, glucosamine, chondroitin, hyaluronic acid, and elastin in their natural ratios. Trials show meaningful joint pain and stiffness improvement in OA within 10 days — much faster than glucosamine alone. Among the more compelling small-dose joint supplements.
- Form
- NEM (Natural Eggshell Membrane) — ESM Technologies' patented form (Move Free, JointGenesis).
- Dose
- 500 mg/day.
- Timing
- With food. AM common.
- Schedule
- Daily.
- Side effects
- Generally very well-tolerated. Egg allergy is the only real concern.
- Interactions
- Generally clean.
- Contraindications
- Egg allergy. Otherwise none.
- Lab markers
- Joint function tracking (WOMAC).
- Food sources
- Eggshell membranes are inside every eggshell — but practically inaccessible as food in usable quantities.
Pairs with
UC-II, glucosamine, omega-3 (joint stack). Collagen peptides.
within Polysaccharides & glycoconjugates