Adipotide (FTPP)

Pro-apoptotic peptidomimetic targeting fat-vasculature prohibitin — rapid weight loss in primate models.

Adipotide works on a completely different principle from the GLP class. Instead of curbing appetite, it targets the blood vessels that feed fat tissue and triggers them to die, effectively starving the fat cells of their supply. In primate studies it caused fast, dramatic fat loss — but it also caused kidney toxicity, which is the dealbreaker. It's a genuinely dangerous, deeply experimental compound, included here for completeness rather than as a realistic option.