Tinnitus desperation is a goldmine for the supplement industry, and almost none of what it sells works. Here's the honest grading — the few things worth a look, and the many that aren't.
Ginkgo biloba, the most-hyped, showed no reliable benefit in the Cochrane review. Zinc and vitamin B12 help only if you are genuinely deficient (test, don't guess). Magnesium is theoretical. Guidelines (AAO-HNS) specifically recommend against ginkgo, melatonin, zinc, and other supplements for treating tinnitus. Evidence ○○○○○ for ginkgo as a treatment
Melatonin is really a sleep aid — it can help tinnitus tolerance when insomnia is part of the picture, with modest supportive data, which is a legitimate but narrow use. N-acetylcysteine (NAC) has some interest for preventing noise damage in high-exposure settings, not for treating established tinnitus. And correcting a documented B12 or zinc deficiency is reasonable — otherwise skip them. Evidence ●●○○○
Direct-to-consumer 'silence the ringing' blends — Quietum Plus, Tinnitus 911, Lipo-Flavonoid — have no credible trials (the one that was tested, Lipo-Flavonoid, failed), fabricated testimonials, and invented 'cured' counts. This is a predatory industry monetising a condition that has no cure. The marketing spend is the tell. Evidence ○○○○○
'Natural' isn't 'safe' or 'proven'
No supplement cures tinnitus, and no forthcoming pill should tempt you to delay the things that work. Spend the money on good earplugs and a CBT course instead — and if you do try a supplement, test for the deficiency first rather than swallowing on hope.
The Tinnitus Guide