Stress & cortisol
- Cross-inhibition
The stress axis (cortisol) and the reproductive axis (testosterone) inhibit each other at the hypothalamus, pituitary and testis. Chronic or severe stress lowers testosterone — and it's reversible, rebounding in recovery. Brief, everyday stress is an unreliable suppressor (sometimes it transiently raises T); the robust effect is from sustained stress. Real, but a modest lever for most men. Evidence ●●●○○