Iron, Serum (Total Iron)

Routine annual

also

What it isThe total amount of iron circulating in blood bound to transferrin. Iron is essential for hemoglobin, myoglobin, and many enzymes.

DoesTransports iron from gut absorption and red cell turnover to bone marrow and other tissues.

GoodMid-range iron with appropriate ferritin signals balanced iron handling.

BadLow serum iron with low ferritin confirms iron deficiency. High iron with high transferrin saturation suggests hemochromatosis.

Standard
Men 65–175 µg/dL; women 50–170 µg/dL.
Optimal
90–140 µg/dL men, 80–130 µg/dL women (narrow target)
Modifiers
Diurnal — peaks early morning; falls with inflammation; rises shortly after iron supplements.

How to optimize

Lifestyle
Same as ferritin.
Diet
Same as ferritin.
Supplements
Same as ferritin.
Peptides
Drugs
IV iron for severe deficiency.