GGT (Gamma-Glutamyl Transferase)

Routine annual

also gamma gt

What it isGGT is a liver and bile duct enzyme that helps the body recycle glutathione, its master antioxidant. It is exquisitely sensitive to alcohol and to oxidative stress in the liver.

DoesTracks alcohol exposure, oxidative stress, and bile flow.

GoodLow GGT signals minimal alcohol exposure, low oxidative stress, and patent bile ducts.

BadElevated GGT marks alcohol use, fatty liver, medication effects, and oxidative stress. Even within the normal range, rising GGT predicts cardiovascular events, type 2 diabetes, and all-cause mortality.

Standard

8–61 U/L men; 5–36 U/L women.

Optimal

10–22 U/L men, 5–15 U/L women (lower is good)

Modifiers

Rises sharply with alcohol; many medications elevate it; iron overload contributes.

How to optimize

Lifestyle: Eliminate alcohol entirely (single biggest mover), Zone 2 cardio, weight loss.
Diet: Cut alcohol, fructose, refined carbs; Mediterranean pattern with cruciferous vegetables (broccoli, kale, brussels sprouts) for liver support.
Supplements: N-acetylcysteine (600mg 2×/day), milk thistle silymarin (200mg 3×/day), choline (500mg/day), magnesium glycinate (300mg/day), B-complex.
Peptides: GLP-1 agonists (via fatty liver improvement).
Drugs: GLP-1 agonists, pioglitazone.

within Liver & Detox