Beta-2 Microglobulin

What it isA small protein found on the surface of nearly all nucleated cells, shed into blood at a steady rate proportional to cell turnover.

DoesActs as a prognostic marker in multiple myeloma and other lymphoid cancers; also reflects kidney.

GoodA low beta-2 microglobulin in a treated myeloma patient signals disease control.

BadElevated beta-2 microglobulin in myeloma predicts worse prognosis. Also rises with chronic inflammation and kidney impairment.