AFP (Alpha-Fetoprotein)

Specialist

also —

What it isAFP is a fetal protein normally present in pregnancy. In adults, it rises with hepatocellular carcinoma and certain germ cell tumors.

DoesScreens for liver cancer in high-risk patients (cirrhosis, chronic hepatitis B/C) and monitors germ cell tumor treatment.

GoodLow AFP in a cirrhotic patient supports surveillance reassurance.

BadRising AFP in chronic liver disease flags possible hepatocellular carcinoma; elevation in young men can signal testicular germ cell tumor.

Standard

<8.3 ng/mL.

Optimal

0–8.3 ng/mL (lower is good)

Modifiers

Elevated in pregnancy normally; benign elevations in chronic hepatitis.

How to optimize

Lifestyle: Hepatitis B vaccination, treat hepatitis C, avoid alcohol in liver disease.
Diet: Mediterranean pattern.
Supplements: —
Peptides: —
Drugs: Antiviral therapy for hepatitis B/C; cancer-directed therapy if indicated.

within Cancer Markers