AST/ALT (De Ritis) Ratio

What it isA simple ratio of AST to ALT that fingerprints the type of liver injury when both enzymes are elevated.

DoesDistinguishes alcoholic liver injury (high ratio) from non-alcoholic fatty liver disease (low ratio) and tracks the progression to fibrosis.

GoodA ratio near 1.0 with both enzymes in the optimal range signals healthy liver biology.

BadA ratio >2 with elevated enzymes strongly suggests alcoholic liver disease; a ratio <1 with elevated enzymes is the fatty liver signature. A rising ratio over time suggests advancing fibrosis.