Passionflower
AnxietySleep
A gentle anxiolytic herb that works through GABA — useful for mild generalised anxiety and as a pre-bed sleep support.
EvidenceModerate
Moderate for generalised anxiety, pre-procedure anxiety, and sleep quality. Effects: hours to days for anxiety; 2 weeks for sleep.
Passiflora incarnata is a flowering vine native to the Americas. Its flavonoids (especially chrysin) modulate GABA-A receptors, producing mild anxiolytic and sedative effects. Small RCTs show comparable anxiety reduction to low-dose benzodiazepines for pre-procedure anxiety, and modest sleep benefit. Gentler than valerian, often combined with it.
- Form
- Passionflower extract standardised to flavonoid content. Tinctures, capsules, and teas all common.
- Dose
- 250–500 mg extract 1–3x daily. 500 mg 30–60 min before bed for sleep.
- Timing
- Anytime for anxiety. PM for sleep.
- Schedule
- Daily or as-needed.
- Side effects
- Generally well-tolerated. Mild drowsiness, dizziness, GI upset.
- Interactions
- Sedatives, MAOIs, anticoagulants — mild additive effects. Anti-anxiety medications — additive.
- Contraindications
- Pregnancy (uterine stimulant). Pre-surgery (stop 1–2 weeks before).
- Lab markers
- Not standard.
- Food sources
- Passionflower tea is the traditional preparation.
Pairs with
Valerian, lemon balm, hops (sleep blend). L-theanine, magnesium (calm stack).
within Herbs & botanicals