Pal Pentapeptide-4 (Matrixyl)

Lipidated procollagen fragment (KTTKS) that stimulates collagen I, III, and fibronectin synthesis. The original Matrixyl.

Matrixyl is the workhorse collagen-building peptide. It's a fragment of collagen itself, attached to a fatty tail so it can penetrate the skin; once there it tricks the skin into thinking its own collagen has broken down and needs replacing, switching on fresh collagen and fibronectin production. It's one of the best-evidenced anti-aging actives for firmness and fine lines, and the backbone of countless serums.