Enclomiphene

SERM (not a peptide) that blocks estrogen at the pituitary to raise endogenous LH and testosterone.

Enclomiphene isn't a peptide — it's a selective estrogen receptor modulator (the "active" isomer of clomiphene). It blocks estrogen's feedback signal at the pituitary, fooling the brain into thinking estrogen is low and ramping up LH and FSH — your body's own instructions to make more testosterone. The big draw versus TRT is that it raises testosterone while preserving fertility and testicular function rather than shutting them down. It's a daily oral, popular for natural-T optimisation and for recovering the axis after a cycle.

Dose
12.5–25 mg oral daily.
Reconstitute
Oral capsule or tablet — no reconstitution.
Schedule
8–12 week cycles, then taper off.
Half-life
~10 hours.
Timing
AM with food.
Risks
Possible mood or vision changes. Estrogen can rise as testosterone rises. Not great for the liver if abused.
Pairs withKisspeptin (combined HPG-axis restoration); standard PCT or testosterone-natural-boost protocol.

within Sexual Health & Reproductive