Vitamin D-Binding Protein

What it isA liver-made carrier protein that binds vitamin D metabolites in circulation, parallel to how SHBG binds sex hormones.

DoesBuffers vitamin D availability to tissues.

GoodA mid-range DBP allows free and bound vitamin D to coexist in healthy balance.

BadGenetic variation in DBP affects bioavailable vitamin D and explains why some people benefit from vitamin D supplementation more than others.