RPR / Syphilis

Routine annual

also rapid plasma reagin

What it isA nontreponemal antibody test that screens for syphilis. Positive results require confirmatory treponemal testing.

DoesDetects antibodies produced in response to syphilis infection.

GoodNonreactive result rules out current syphilis.

BadReactive results trigger confirmatory testing and treatment if active syphilis is confirmed. Untreated syphilis progresses through stages with serious neurological and cardiovascular complications.

Standard
Nonreactive.
Optimal
Nonreactive (lower is good)
Modifiers
Titer falls with successful treatment.

How to optimize

Lifestyle
Safer sex practices.
Diet
Supplements
Peptides
Drugs
Penicillin G (single dose for early syphilis; multiple doses for late/latent).