Prolactin (in men)

Advanced wellness

also prl

What it isA pituitary hormone primarily known for milk production in women but present and active in men too.

DoesSuppresses gonadotropin-releasing hormone, which lowers LH/FSH and therefore testosterone. Also influences libido, refractory period after orgasm, and immune.

GoodA mid-low prolactin signals an unobstructed gonadal axis and intact libido.

BadElevated prolactin in men suppresses testosterone, causes erectile dysfunction, low libido, and possibly gynecomastia. Very high levels suggest a pituitary tumor (prolactinoma).

Standard

<15 ng/mL.

Optimal

3–10 ng/mL (lower is good within range)

Modifiers

Rises with stress, sleep, recent nipple stimulation, certain medications (antipsychotics, some antidepressants).

How to optimize

Lifestyle: Stress management; quality sleep; address dopaminergic balance.
Diet: —
Supplements: Vitamin B6 (P5P, 25–50mg/day) and zinc may help; vitex (chasteberry) for some.
Peptides: —
Drugs: Cabergoline (dopamine agonist) for prolactinoma; identify and replace prolactin-raising medications.

within Men's Hormones