Glycation Gap

What it isA calculated discrepancy between the A1c the body actually shows and the A1c predicted from a fructosamine measurement. The gap exposes hidden quirks in how an individual glycates proteins or how long their red cells live.

DoesQuality-checks A1c by comparing it against a different glycation marker.

GoodA near-zero gap means A1c can be trusted as an honest mirror of average glucose.

BadA large positive gap suggests A1c is overstating true glucose exposure (long-lived red cells, faster glycation); a large negative gap suggests it understates (short-lived cells, hemoglobinopathy). Both signal that you need a backup marker before making decisions.