Aldosterone

Specialist

also —

What it isAldosterone is the adrenal hormone that regulates sodium retention and potassium excretion in the kidney, controlling blood volume and blood pressure.

DoesDrives sodium reabsorption (and water with it) in the distal nephron, expanding blood volume.

GoodA mid-range aldosterone signals balanced volume control.

BadElevated aldosterone drives hypertension, low potassium, and cardiovascular damage. Primary aldosteronism is an underdiagnosed cause of resistant hypertension.

Standard

Upright 4–31 ng/dL.

Optimal

6–18 ng/dL upright (narrow target)

Modifiers

Posture-dependent; rises with sodium restriction.

How to optimize

Lifestyle: Manage blood pressure; moderate sodium without extreme restriction.
Diet: Mediterranean-pattern moderate sodium.
Supplements: Magnesium glycinate (300mg/day) if elevated; potassium adequacy.
Peptides: —
Drugs: Spironolactone, eplerenone, finerenone block aldosterone.

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